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Stimulation of rat pancreatic exocrine secretion by urocortin and corticotropin releasing factor

โœ Scribed by Eduardo A Guzman; Weizhen Zhang; Theodore R Lin; Michael W Mulholland

Book ID
117408551
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
321 KB
Volume
24
Category
Article
ISSN
0196-9781

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The mitogenic effect of corticotropin-releasing factor (CRF) on rat lymphocytes was investigated. When rat splenocytes were cultured for 48 hr with CFR, a dosedependent increase in incorporation of 3H-thymidine (3H-Tdr) was observed, with a maximal response at 10 nM CRF. Comparison of the proliferat