In vitro inhibition of aggrecanase activ
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JΓΌrgen Steinmeyer; Jens Kordelle; Henning StΓΌrz
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Article
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2010
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Elsevier Science
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English
β 145 KB
π 1 views
## Abstract Tetracyclines were reported to slow down the progression of cartilage damage both in an animal model of osteoarthritis (OA) and in humans. In search for the underlying mechanisms we examined whether tetracyclines possess an inhibitory potential on the activity of aggrecanases and inflam