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Stimulation of protein kinase B and p70 S6 kinase by the histamine H1 receptor in DDT1MF-2 smooth muscle cells

✍ Scribed by John M Dickenson


Book ID
110007252
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
328 KB
Volume
135
Category
Article
ISSN
0007-1188

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The A 2A adenosine receptor is prototypically coupled to stimulation of adenylyl cyclase by means of G s . However, in human endothelial cells, adenosine stimulates proliferation and mitogen-activated protein kinase (MAP kinase) by means of the A 2A receptor in a manner that is independent of cAMP.