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Stimulation of non-transferrin iron uptake by iron deprivation in K562 cells

✍ Scribed by Jan Kovar; Jitka Neubauerova; Marketa Cimburova; Jaroslav Truksa; Kamila Balusikova; Jiri Horak

Book ID
116304172
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
276 KB
Volume
37
Category
Article
ISSN
1079-9796

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The effect of lead on cellular iron metabolism has been investigated using human erythroleukemia (K562) cells. When the cells were cultured with 100 ?t~ Pb 2+ for 48 h, the rate of Cellular iron uptake from transferrin decreased to 46% of that in untreated cells. Scatchard analysis of the binding da