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Stimulation of Na+/H+Antiport is an Early Event in Hypertrophy of Renal Proximal Tubular Cells

✍ Scribed by Leon G. Fine, Behnam Badie-Dezfooly, Andrew G. Lowe, Ali Hamzeh, John Wells and Saleh Salehmoghaddam

Book ID
123631828
Publisher
National Academy of Sciences
Year
1985
Tongue
English
Weight
773 KB
Volume
82
Category
Article
ISSN
0027-8424

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Cl(-) /HCO (3)(-) exchanger and Na(+) /H(+) exchanger 3 are the main transporters responsible for NaCl reabsorption in kidney proximal tubules (PT). It is well accepted that membrane exchangers can be regulated by reactive oxygen species (ROS). In the kidney, ROS are known to contribute to decreases