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Stimulation of melanogenesis by DNA oligonucleotides: effect of size, sequence and 5′ phosphorylation

✍ Scribed by Hadshiew, Ina M; Eller, Mark S; Gasparro, Frank P; Gilchrest, Barbara A

Book ID
118050189
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
407 KB
Volume
25
Category
Article
ISSN
0923-1811

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## Abstract ## Background Single‐stranded oligonucleotides (ssODN) can induce site‐specific genetic alterations in selected mammalian cells, but the involved mechanisms are not known. ## Methods We corroborate the potential of genomic sequence correction by ssODN using chromosomally integrated m