Stimulation of macromolecular synthesis by endotoxin-treated 3T6 fibroblasts
โ Scribed by J. J. Aleo
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 239 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Earlier work showed that thrombin stimulates proliferation of human fibroblasts in serumfree medium. This work demonstrates (1) that thrombin has to be present during most or all of the G1 period to ensure maximal DNA synthesis, (2) that DNA synthesis increases about three hours later a
## Marylmd 2 7224 In Swiss 3T3. murine fibroblasts, interleukin 1 (IL-1) and bradykinin stimulate prostdglandin E, (PGE,) synthesis. However, in the present study, we found that neither agonisi stimulated PGE, synthesis in BALBic 3T3 murine fibroblasts, this in spite of expression of similar numbe
Rapidly growing Swiss 3T3 fibroblasts possess a bumetanide-sensitive K + transport system that is dependent on both Na+ and CI-ions; a smaller bumetanide-insensitive component of K + transport is also present. In cells brought to the quiescent state by 8-11 days of incubation without a medium change
In this work, we demonstrate that a nonlethal dose of arsenite administered to quiescent C3HlOT112 fibroblasts can enhance the mitogenic effect of suboptimal concentrations of serum. The mitogenic effect was dependent on the serum concentration and on the time interval between the administration of