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Stimulation of inositol phosphate production in clonal HSDM1C1 cells by endothelins and sarafotoxin

✍ Scribed by Najam A. Sharif; Roger L. Whiting

Book ID
115781636
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
520 KB
Volume
40
Category
Article
ISSN
0006-2952

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Cultured astrocytes express bradykinin (BK) receptors, which are coupled to phospholipase C (PLC) through G-protein to mediate phosphoinositide (PI) hydrolysis. The regulation of this BK receptor-G protein-PLC pathway by CAMP and endothelin-1 (ET-1) was explored by short-term (20 min) and long-term