Stimulation of human lymphocytes with irradiated cells of the autologous Epstein-Barr virus-transformed cell line: I. Virus-specific and nonspecific components of the cytotoxic response
โ Scribed by L.E. Wallace; A.B. Rickinson; M. Rowe; D.J. Moss; D.J. Allen; M.A. Epstein
- Book ID
- 113132267
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 890 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0008-8749
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## Abstract EBVโspecific cytotoxic T cells (Tc)^1^ induced __in vitro__ have continuously proliferated __in vitro__ for over 9 months. The longโterm maintenance of the Tc growth was dependent on periodic supplementation of both irrediated EBVโtransformed autologous lymphoblastoid cell line (LCL) ce
## Abstract Unfractionated mononuclear (UM) cells and T cells freshly prepared from the blood of adult donors were coโcultivated in microtest plate wells with progressively lower numbers of cells from the autologous EBโvirusโtransformed Bโcell line. The fresh cells present in coโcultures from EB vi