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Stimulation of human airway epithelial cells by platelet activating factor (PAF) and arachidonic acid produces 15-hydroxyeicosatetraenoic acid (15-HETE) capable of contracting bronchial smooth muscle

โœ Scribed by C.K.W. Lai; S.T. Holgate


Publisher
Elsevier
Year
1992
Tongue
English
Weight
132 KB
Volume
5
Category
Article
ISSN
0952-0600

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Stimulation of human airway epithelial c
โœ H Salari; R.R Schellenberg ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier ๐ŸŒ English โš– 532 KB

Human airway epithelial cells grown to confluence were incubated with varying concentrations (10-100 microM) of arachidonic acid or platelet activating factor (PAF) for periods of 30 min to 24 h. Both stimuli caused the production of 15-hydroxyeicosatetraenoic acid (15-HETE) by epithelial cells as d