Stimulation of guanylate cyclase by atrial natriuretic factor in isolated human glomeruli
โ Scribed by Nicole Ardaillou; Marie-Paule Nivez; Raymond Ardaillou
- Book ID
- 115917116
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 463 KB
- Volume
- 189
- Category
- Article
- ISSN
- 0014-5793
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The putative 'second messenger' of certain atrial natriuretic factor (ANF) signal transductions is cyclic GMP. Recently, we purified a 180-kDa protein, apparently containing both ANF receptor and guanylate cyclase activities, and hypothesized that this is one of the cyclic GMP transmembrane signal t
## Abstract Atrial natriuretic peptide (ANP), found in mammalian ovarian granulosa cells and oocytes (Kim et al., 1992, 1993), induces the human acrosome reaction (Anderson et al., 1994). The purpose of the present study was to determine whether ANP, as eggderived peptides from sea urchins, can act