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Stimulation of growth of human breast cancer cell lines in culture by linoleic acid

✍ Scribed by David P. Rose; Jeanne M. Connolly


Book ID
115761952
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
392 KB
Volume
164
Category
Article
ISSN
0006-291X

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Diets rich in linoleic acid (LA) stimulate the metastasis of MDA-MB-435 human breast cancer cells from the mammary fat pads of nude mice. This omega-6 fatty acid is metabolized to various cyclo-oxygenase and lipoxygenase products, several of which have been previously associated with tumor cell inva