Stimulation of DNA Synthesis in Hepatocytes by Hepatocyte Growth Factor Bound to Extracellular Matrix
โ Scribed by A. Masumoto; N. Yamamoto
- Book ID
- 115572732
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 249 KB
- Volume
- 191
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
## Abstract The effect of hepatocyte growth factor/scatter factor (HGF/SF) on the proliferation of human skin fibroblasts was examined. At concentrations above 1.0 ng/ml, both native and recombinant human HGF/SF stimulated the DNA synthesis determined by [^3^H]thymidine incorporation, which was com
Studies were carricd out to analyze how different extracellular matrix (ECM) moleculcs regulate hepatocyte growth and differentiation. Freshly isolated rat hepatocytes were cultured on non-adhesive plastic dishes that were pre-coated with defined densities of eithcr laminin, fibroncctin, type I coll
We have reported that infusion of recombinant human hepatocyte growth factor (rhHGF) stimulates liver regeneration after hepatectomy in cirrhotic rats and increases the level of serum lipids and secretion of very-low density lipoprotein (VLDL). Studies were now performed to determine whether rhHGF d