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Stimulation of cholinergic nerves in dog intestine by adenine nucleotides

✍ Scribed by Margaret G. Northway; Thomas F. Burks


Book ID
115876031
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
635 KB
Volume
65
Category
Article
ISSN
0014-2999

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The effect of 5'-N-ethylcarboxamidoadenosine (NECA) on rat bronchial smooth muscle was examined in vitro. Both the nerve mediated muscle contraction induced by electrical stimulation and the potassium evoked release of [3H]ACh were enhanced by NECA. The apparent affinity (EC50) of NECA in the contra