Stimulation of carbonic anhydrase in osteoclasts by parathyroid hormone
β Scribed by R. E. Anderson; W. S. S. Jee; D. M. Woodbury
- Book ID
- 110554290
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 544 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1432-0827
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π SIMILAR VOLUMES
Calvaria from newborn rats were used to localize carbonic anhydrase isoenzymes in bone tissue. Highly sensitive peroxidase-antiperoxidase method revealed strong reaction of high-active C form of carbonic anhydrase exclusively in the osteoclasts. There was no reaction in osteoblasts or fibroblasts bu
There have been several lines of evidence that parathyroid hormone (PTH) stimulates production of insulinlike growth factor I (IGF-I) in bone and that IGF-I stimulates osteoclast formation. Thus, the present study was performed to clarify the possible role of IGF-I in PTH-stimulated osteoclastlike c
## Abstract A number of previous investigations have indicated that the pituitary may directly stimulate of secretion of parathyroid hormone. Others have disagreed. With the recent development of an in vitro bovine parathyroid perfusion system, the direct effect of suspected secretagogues can be as