Insulin-like growth factor I1 is believed to play an important role in fetal growth and development. The insulin-like growth factor I1 gene expression is tissue specific and developmentally regulated. We have previously shown an enhanced level of insulin-like growth factor I1 messenger RNA and prote
Stimulation of Bone FormationIn Vivoby Insulin-Like Growth Factor-II in Rats
β Scribed by M. Ishibe; T. Ishibashi; K. Kaneda; T. Koda; R. N. Rosier; J. E. Puzas
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 271 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1432-0827
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We have previously shown that insulin-like growth factor II (IGF-II) is produced by bone cells and that IGF-II stimulates cell proliferation and collagen synthesis in bone cells. We now extend these in vitro findings by demonstrating specific IGF-I1 binding to bone cells derived from newborn mouse c
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