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Stimulation of be-ta1 integrin down-regulates ICAM-1 expression and ICAM-1 dependent adhesion of lung cancer cells through focal adhesion kinase

โœ Scribed by Yasuda, M; Tanaka, Y; Sugaya, M; So, T; Eifuku, R; Imahayashi, S; Yoshimatsu, T; Oyama, T; Eto, S; Yasumoto, K


Book ID
118570215
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
113 KB
Volume
29
Category
Article
ISSN
0169-5002

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CHO cells expressing a 5 b 1 integrin are more resistant to apoptosis and express more Bcl-2 than the same cells engineered to express a v b 1 or cytoplasmically truncated a 5 Dcb 1 integrin as their main fibronectin receptor. The Bcl-2 up-regulation by a 5 b 1 is mediated, at least in part, by the