Preparation of 11C-labelled SCH 23390 fo
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Christer Halldin; Sharon Stone-Elander; Lars Farde; Erling Ehrin; Karl-Johan Fas
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Article
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1986
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Elsevier Science
β 307 KB
The dopamine D-1 receptor antagonist, SCH 23390 ((R)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3- benzazepin-7-ol), was labelled by alkylation of the desmethyl compound SCH 24518 ((R)-(+)-8-chloro-2,3,4,5-tetrahydro-5-phenyl-1H-3-benzazepin-7- ol) with [11C]methyl iodide. A multivariate o