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Stimulation by Insulin of a Serine Kinase in Human Platelets That Phosphorylates and Activates the cGMP-Inhibited cAMP Phosphodiesterase

✍ Scribed by P. Lopezaparicio; P. Belfrage; V.C. Manganiello; T. Kono; E. Degerman


Book ID
115573129
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
462 KB
Volume
193
Category
Article
ISSN
0006-291X

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A new cGMP phosphodiesterase isolated fr
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## Abstract The biochemical differences among cGMP phosphodiesterases in platelets have not been thoroughly examined, primarily due to the lack of sufficient purified material. This report describes a simple method developed to isolate specific bovine platelet cGMP phosphodiesterase. This enzyme is