On the mechanism of hormone action in 7,
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Gordon H. Sasaki; Dr. Benjamin S. Leung
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Article
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1975
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John Wiley and Sons
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English
⚖ 552 KB
The presence of ER in DMBA-tumors was demonstrated by the use of dextrancharcoal assay, sephadex chromatography, sucrose gradient sedimentation, and organ culture techniques. It was found that tumors have binding sites ranging from 10-" to 10-l' moles/mg protein, and a dissociation constant of ER 10