The high incidence of elevated immunoglobulin (Ig)G anti-GQ1b antibody in sera from patients with acute phase Miller-Fisher syndrome (MFS) was first reported by Chiba et al. 1 and later confirmed by two other groups. 3,4 Chiba et al. 2 pointed out that anti-GQ1b IgG antibody is associated specifical
Stimulated single-fiber electromyography in Lambert-Eaton myasthenic syndrome before and after 3,4-diaminopyridine
โ Scribed by Menachem Sadeh; Yaron River; Zohar Argov
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 188 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0148-639X
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โฆ Synopsis
A patient with LEMS unrelated to cancer was studied by
CASE OF THE MONTH
stimulated single-fiber electromyography (SFEMG) before and 3 months after the onset of therapy with 3,4-diaminopyridine. All end-plates showed Section Editors a progressive reduction in blockings and jitter with the increase in stimulation rate. Treatment significantly corrected this feature, but the overall pattern of Robert C. Griggs, MD frequency-improved jitter remained. Such widespread finding is rare but Rochester, New York diagnostic for Lambert-Eaton myasthenic syndrome. Stimulated SFEMG
๐ SIMILAR VOLUMES
Diaminopyridine (3,4-DAP) is known to be beneficial in the symptomatic treatment of the Lambert-Eaton myasthenic syndrome (LEMS). The effects of 3,4-DAP on the decay of postexercise augmentation were observed in 6 patients with LEMS. After 10 s maximal voluntary contraction, the amplitude of the co