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Stimulated Expression of mRNAs in Activated T Cells Depends on a Functional CRM1 Nuclear Export Pathway

✍ Scribed by Sylvia Schütz; Jan Chemnitz; Christiane Spillner; Marcus Frohme; Joachim Hauber; Ralph H. Kehlenbach

Book ID: 116662900
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 473 KB
Volume: 358
Category: Article
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2006.02.041

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## Abstract The basis of the adjuvant effect of IL‐1 on the clonal expansion of Ag‐specific CD4 T cells was measured __in vivo__ using the TCR transgenic T cell adoptive transfer method. Injection ofAg plus IL‐1 caused naive CD4 T cells to proliferate to a greater extent than did injection of Ag al