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Stiff-man syndrome, immunoglobulin therapy in seronegative glutamic acid decarboxylase antibodies

✍ Scribed by G.R. Hayat; S. Cruz-Flores


Book ID
115871145
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
167 KB
Volume
98
Category
Article
ISSN
0013-4694

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Glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the conversion of glutamate to β₯-aminobutyric acid (GABA). Anti-GAD antibody (GAD-Ab) is considered to be a marker for stiff person syndrome (SPS), 1 insulin-dependent diabetes mellitus (IDDM), and polyendocrine autoimmune syndrome. 2 Add