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STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications

✍ Scribed by Tuveson, David A; Willis, Nicholas A; Jacks, Tyler; Griffin, James D; Singer, Samuel; Fletcher, Christopher DM; Fletcher, Jonathan A; Demetri, George D


Book ID
110065951
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
225 KB
Volume
20
Category
Article
ISSN
0950-9232

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## Abstract ## Background and objective to analyze the frequency and spectrum of KIT and platelet‐derived growth factor receptor‐alpha (PDGFRA) gene in a large series of study and to explore the clinical implication of mutations in the gastrointestinal stromal tumors (GISTs) in China. ## Method