High specific activity tritium labeling
✍
Steve A. de Keczer; Tim S. Lane; Tatyana Voronin; Mohammad R. Masjedizadeh
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
French
⚖ 120 KB
The octahydroindenone intermediate was tritium labeled using T 2 O isotope exchange labeling, and then elaborated to the vitamin D derivative RO275646. Though this method of labeling was expected to give the minor isomer, it was the shortest and most convenient route to the high specific activity me