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Sterols. CXXXIX. Sapogenins. LIX. The Bio-reduction of 4-Dehydrotigogenone 1,1a

✍ Scribed by Marker, Russell E.; Wittbecker, Emerson L.; Wagner, R. B.; Turner, D. L.


Book ID
118744315
Publisher
American Chemical Society
Year
1942
Tongue
English
Weight
558 KB
Volume
64
Category
Article
ISSN
0002-7863

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a chiral sulfoxide induced high stereoselectivity in the D1BAL-H reduction of a methyl ketone located in the T position as a result of a 1,4-asymmetric induction. Addition of a lanthanide triflate or cerium chloride completely reversed the stereoselectivity.