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Sterol Regulatory Element-Binding Protein-2 modulates human brain acyl-CoA hydrolase gene transcription

✍ Scribed by Mitsuhiro Takagi; Fumitaka Suto; Tetsuya Suga; Junji Yamada


Book ID
106457460
Publisher
Springer
Year
2005
Tongue
English
Weight
998 KB
Volume
275
Category
Article
ISSN
0300-8177

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Sterol regulatory element binding protein 1 (SREBP-1) transcription factors play a key role in energy homeostasis by regulating genes involved in both carbohydrate and lipid metabolism, and in adipocyte differentiation. The 5' end of the mRNA-encoding SREBP-1 exists in two forms, designated 1a and 1