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Sterol, Protein and Lipid Trafficking in Chinese Hamster Ovary Cells with Niemann-Pick Type C1 Defect

✍ Scribed by Nina H. Pipalia; Mingming Hao; Sushmita Mukherjee; Frederick R. Maxfield


Book ID
111268206
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
954 KB
Volume
8
Category
Article
ISSN
1398-9219

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## Abstract A mutant (A204) of Chinese hamster ovary cells (CHO‐K1), which is deficient in dihydroorotate (DHO) dehydrogenase (E.C. 1.3.3.1) activity, has been isolated by a replica plating procedure. The mutant does not show a requirement for exogenously added pyrimidines. Examination of intact ce