Sterol esters of Phycomyces blakesleeanus
β Scribed by E.Ian Mercer; Kim Bartlett
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 674 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0031-9422
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Mutants resistant to nikkomycin, an inhibitor of chitin biosynthesis, were isolated after exposure of wild-type spores of the fungus Phycomyces blakesleeanus to N-methyl-N'-nitro-N-nitrosoguanidine. Genetic analysis revealed that nikkomycin resistance was due to mutations in a single gene, chsA. Mut
Complementation tests among Phycomyces auxotrophic strains revealed the existence of four genes with mutants requiring riboflavin, three genes with purine auxotrophs, two with nicotinic acid auxotrophs, and two with lysine auxotrophs. A total of 134 sexual crosses between strains carrying mutations