𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Steroids. Part I. Selective Hydrogenation of Ergosterol and its Acetate

✍ Scribed by Wadie Tadros; Adel Louis Boulos


Book ID
102855472
Publisher
John Wiley and Sons
Year
1975
Tongue
German
Weight
520 KB
Volume
58
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Selective hydrogenation of ergosterol or its acetate in solution in different solvents over Raney nickel to give 5α‐ergosta‐7,22‐dien‐3β‐ol or its acetate can be controlled by the addition of paraformaldehyde, acetaldehyde, benzaldehyde, 4‐dimethylaminobenzaldehyde, and dimethylaniline, the latter 2 giving the best yield. When using pure solvents 5α‐ergost‐7‐en‐3β‐ol or its acetate can be obtained in almost quantitative yield.


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