✦ LIBER ✦
Steroids I. Alkylation of β-ketoesters via their Cu(II) enolates in aqueous media. Application of the synthesis of C-18 functionalized steroids via the torgov approach.
✍ Scribed by Plato A. Magriotis; William V. Murray; Francis Johnson
- Book ID
- 104220741
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 216 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Three steroidal pentaenes ( a-r;) have been synthesized, the key step being the 81 alkylatlon of the Cu(I1) the ates of the ring D precursors ($22) by the isothiouronium acetate J, in aqueous solution.