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Steroids as Chiral Ligands: Different Molecular and Crystal Structures of Copper(II) Complexes of Mono- and Dideprotonated 16β-Salicylideneimino-17β-hydroxy-3-methoxyestra-1,3,5(10)-triene

✍ Scribed by Krieg, Reimar ;Dubs, Manuela ;Görls, Helmar ;Schönecker, Bruno


Publisher
Wiley (John Wiley & Sons)
Year
1996
Tongue
English
Weight
476 KB
Volume
129
Category
Article
ISSN
0009-2940

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✦ Synopsis


Steroids / Chiral amino alcohols / Copper(I1) salicylideneimine complexes / X-ray analysis

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The steroidal 16~-salicylideneimino-l7~-hydroxy compound 1, synthesized from the corresponding 16p, 17P-amino alcohol, served as a new tridentate chiral ligdnd for Cu'+-complexation. The X-ray data for 1 and for two dimeric copper complexes 2 and 3 are presented and discussed. Using copper(I1) acetate for complexation, dideprotonation of 1 is observed. The neutral complex 2 obtained is characterized by a central planar four-membered copper-oxygen ring. The cycloaliphatic 17 P-oxygen anions are bridging atoms; the