Steroidogenic acute regulatory protein in the brain
โ Scribed by E. Lavaque; A. Sierra; I. Azcoitia; L.M. Garcia-Segura
- Book ID
- 116787159
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 118 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0306-4522
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## Abstract We studied the effect of the adrenocorticotropin hormone (ACTH) on the expression of the steroidogenic acute regulatory protein (StAR) in vivo in rat and hamster adrenals and also in transfection experiments using COSโ1 cells. In vivo, ACTH increased the level of StAR mRNA within 30โ60
In response to trophic hormone stimulation of steroidogenic adrenal and gonadal cells, the acute biosynthesis of steroid hormones occurs in the order of minutes to tens of minutes and can be contrasted to chronic regulation, which occurs on the order of hours. The steroidogenic acute regulatory (StA