✦ LIBER ✦
Steroide und Sexualhormone 256. Mitteilung 1. Quassinoide Bitterstoffe I 1-Oxo-2-methoxy-4α-methyl-17β-hydroxy-Δ2-5α-androsten als Modell für den Ring A des Quassins
✍ Scribed by Hans Jörg Koch; Hans Pfenninger; Walter Graf
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- German
- Weight
- 647 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Starting from 3‐oxo‐17β‐hydroxy‐Δ^1^‐5α‐androstene (2b) the preparation of 1‐oxo‐2‐methoxy‐4α‐methyl‐17β‐hydroxy‐Δ^2^‐5α‐androstene (9), a compound with the ring A structure of quassine (1) is described. The key problem of the reaction sequence is shown to be the monomethylation at C(4).