Conformations of Anaesthetic Steroids: a
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Lee Fielding; Niall Hamilton; Ross McGuire
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Article
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1997
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John Wiley and Sons
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English
⚖ 350 KB
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The completely assigned 1H and 13C NMR spectra of the title diastereoisomers in solutions of and CDCl 3 are reported. NOE experiments show that these molecules adopt speciÐc conformations with no rota-DMSO-d 6 tion about the C-2ÈN bond in either solvent. In ring A of the steroid is in a twist-boat c