✦ LIBER ✦
Steroid sulphatase levels are higher in males than in females of the root vole (Microtus oeconomus)
✍ Scribed by Ulf H. Wiberg; Karl Fredga
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 600 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
✦ Synopsis
Steroid sulfatase (STS; EC 3.1.6.2) levels were assayed in cultured fibroblasts of root voles captured in the wild. Four independent experiments were performed using two different substrates (DHEAS and E1S). Evidence is presented that in this species, STS levels are significantly higher in males than in females (ratio 1.6:1). We discuss our findings on a comparative basis and suggest that in the root vole the STS gene(s) is X- and Y-linked (as in the mouse) and that it is subject to X-inactivation, or partially so, on one of the X chromosomes in the female.