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Steroid-responsive pure red cell aplasia associated with natural killer cell lymphocytosis

โœ Scribed by Dr. Ayalew Tefferi; Kevin P. Windebank; Michael H. Veeder; Joseph M. Kiely

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
193 KB
Volume
31
Category
Article
ISSN
0361-8609

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โœฆ Synopsis

A patient with pure red cell aplasia and expansion of the peripheral blood natural killer (NK) cell population is described. Despite normal absolute and differential leukocyte counts, NK cells were increased at diagnosis and at relapse. Furthermore, these cells were not morphologically recognizable on the peripheral blood smear examination. A favorable clinical response to glucocorticoid therapy was accompanied by a decrease in NK cells.

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Acute pure red cell aplasia associated with allopurinol therapy
โœ Lin, Ying-Wei; Okazaki, Shin; Hamahata, Keigo; Watanabe, Ken-ichiro; Usami, Ikuy ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 32 KB ๐Ÿ‘ 1 views

Several investigators have reported patients with acute pure red cell aplasia (PRCA) caused by anticonvulsants, antibiotics, or antithyroid agents. Allopurinol is known to be a causative agent of aplastic anemia, but there have been few reports of acute PRCA induced by allopurinol. We describe here