Steroid receptors in dimethylhydrazine-induced colon carcinogenesis
โ Scribed by Emi Odagiri; Kazuko Jibiki; Yoh Kato; Saeko Nakamura; Sen-Ichi Oda; Reiko Demura; Hiroshi Demura
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 715 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0008-543X
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Tumors from patients with primary colon cancer were studied for the presence of steroid hormone receptors for estrogen (EJ, progesterone (Prog), dihydrotestosterone (DHT) and glucocorticoid. Ten of 33 (30%) tumors contained high affinity E2 receptors. Four were males and six females with positive as
The complement of nuclear non-histone proteins in epithelial cells of the colon is progressively altered during the course of carcinogenesis induced by 1, 2-dimethylhydrazine, until finally the nuclear proteins of tumor cells are easily distinguishable from those of the surrounding normal tissue. Th