Steroid Hormones and Cell Cycle Regulation

✍ Scribed by Nancy L. Weigel, Ramesh Narayanan (auth.), Kerry L. Burnstein (eds.)

Publisher: Springer US
Year: 2002
Tongue: English
Leaves: 264
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

From the tissue culture dish to genetically modified mice, this volume explores the long recognized role of steroid hormones in regulating cell proliferation and differentiation. Many striking effects of steroid hormones are apparent during development and neoplasia and these topics are covered extensively. Several chapters address the pharmacological uses of steroid and related hormones, their analogs and antagonists in controlling growth of endocrine cancers. This book also highlights the complex role of cross talk between steroid hormones and signals initiated at the cell surface in the regulation of cell cycle in hormone responsive tissues.

✦ Table of Contents

Front Matter....Pages i-xi
Mechanisms of Steroid Receptor and Growth Factor Cross Talk....Pages 1-18
Regulation of G1 to S Phase Transition by Adhesion and Growth Factor Signaling....Pages 19-32
Control of Mammary Epithelial Cell Proliferation: The Unique Role of the Progesterone Receptor....Pages 33-55
Estrogen/Estrogen Antagonist Regulation of the Cell Cycle in Breast Cancer Cells....Pages 57-71
Prostate Gland Development and Estrogenic Imprinting....Pages 73-89
Androgen Mediated Regulation of the G1-S Transition in Prostate Cancer....Pages 91-110
Steroid Hormone and Growth Factor Interaction in the Regulation of Cell Cycle Progression....Pages 111-135
Glucocorticoid Regulation of Cell Proliferation....Pages 137-146
Vitamin D Regulation of Cell Cycle and Differentiation in Myeloid Cells....Pages 147-171
Antiproliferative Effect of Vitamin D in Prostate Epithelial Cells....Pages 173-190
Regulation of the Cell Cycle by Peroxisome Proliferator — Activated Receptor Gamma (PPARγ)....Pages 191-205
Regulation of Glucocorticoid Receptor Function During the Cell Cycle....Pages 207-221
Interaction of Cell Cycle Regulatory Proteins with the Androgen Receptor....Pages 223-238
Cyclin Dependent Kinase Regulation of Estrogen Receptor Phosphorylation and Transcriptional Activation....Pages 239-257
Back Matter....Pages 259-262

✦ Subjects

Diabetes; Oncology; Life Sciences, general; Pharmacology/Toxicology; Gynecology

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