Sterile abscess formation associated with depot leuprorelin acetate therapy for central precocious puberty

✍ Scribed by Stephanie R Johnson; Richard C Nolan; Maree T Grant; Glynis J Price; Aris Siafarikas; Lewis Bint; Catherine SY Choong

• Book ID: 115171411
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 272 KB
• Volume: 48
• Category: Article
• ISSN: 1034-4810
• DOI: 10.1111/j.1440-1754.2011.02083.x

✦ Synopsis

Abstract

We describe a case of an 8 year old girl with central precocious puberty. She was commenced on 3 monthly intramuscular depot Leuprorelin acetate therapy, as a result of which she developed sterile abscesses. She was converted to daily subcutaneous Leuprorelin acetate therapy with no recurrence of the abscesses. The possible mechanisms for this reaction are described in the article.