Steric tuning of C2-symmetric chiral N-heterocyclic carbene in gold-catalyzed asymmetric cyclization of 1,6-enynes
β Scribed by Ken-ichi Yamada; Yasumasa Matsumoto; Khalid B. Selim; Yasutomo Yamamoto; Kiyoshi Tomioka
- Book ID
- 113929431
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- French
- Weight
- 349 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
Chiral C 2 -symmetric N-heterocyclic carbenes (NHCs) were tested for their stereocontrolling abilities in gold(I)-catalyzed asymmetric cyclization of 1,6-enynes giving the corresponding cyclopentane derivatives with moderate enantioselectivity of up to 59%.
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