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Steric interactions in 2-substituted imidazoles. The molecular structure of 1-methyl-2-phenylimidazole and 1-methyl-4-phenylimidazole

✍ Scribed by Wendy A. Hallows; Gene B. Carpenter; Karen A. Pevear; D. A. Sweigart

Book ID
112130970
Publisher
Journal of Heterocyclic Chemistry
Year
1994
Tongue
English
Weight
211 KB
Volume
31
Category
Article
ISSN
0022-152X

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## Abstract magnified image Oxidation of metronidazole (**4**) with sodium dichromate yielded the corresponding 2‐(2‐methyl‐5‐nitro‐1__H__‐imidazol‐1‐yl)acetic acid (**5**) which was esterified with 1‐butanol to give butyl 2‐(2‐methyl‐5‐nitro‐1__H__‐imidazol‐1‐yl)acetate (**8**). Reaction of the l