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Steric effects in enyne-allene thermolyses: Switch from the Myers-Saito reaction to the C2C6-cyclization and DNA strand cleavage

✍ Scribed by Michael Schmittel; Susanne Kiau; Torsten Siebert; Marc Strittmatter


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
229 KB
Volume
37
Category
Article
ISSN
0040-4039

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Ring Strain Effects in Enyne-Allene Ther
✍ Michael Schmittel; Jens-Peter Steffen; Dominik Auer; Michael Maywald 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 485 KB

The mode of the thermal cyclization of enyne-allenes 1 depends on ring strain effects: when the ene functionality is part of a benzene, cyclohexene or cycloheptene ring the novel C2-C6biradicrd cyclization is observed, while when it is part of a cyclopentene ring the Myers-Saito cycloaromatization i