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Steric Aspects of Agonism and Antagonism at β-Adrenoceptors: Experiments with the Enantiomers of Terbutaline and Pindolol

✍ Scribed by Jeppsson, A.-B. ;Johansson, U. ;Waldeck, B.


Book ID
118715666
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
488 KB
Volume
54
Category
Article
ISSN
0001-6683

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The enantiomers of formoterol (R;R and S S ) and their diastereomers (RS and SR) were synthesized and purified using a new procedure which required the preparation of the (RR)and (SS)-forms of N-(l-phenylethyl)-N-(l-(p-methoxyphenyl)-2-propyl)-amine as important intermediates. The enantiomeric purit