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Steric and physicochemical studies of decahydroisoquinolines possessing antiarrhythmic activity

✍ Scribed by Ian W. Mathison; Phillip H. Morgan; Richard R. Tidwell; Charles R. Handorf


Book ID
102407098
Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
378 KB
Volume
61
Category
Article
ISSN
0022-3549

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Arylpiperazines represent one of the most studied classes of Ξ±1 -adrenoceptor (Ξ±1 -AR) antagonists. Currently, Ξ±1 -AR antagonists are useful in the treatment of benign prostatic hyperplasia, lower urinary tract symptoms or cardiac arrhythmia. The activity of various derivatives of 1-[3-(4-arylpipera