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Stereospecificity in [2 + 2] cycloaddition of benzyne and ketene silyl acetal

โœ Scribed by Takamitsu Hosoya; Takayuki Hasegawa; Yokusu Kuriyama; Keisuke Suzuki


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
217 KB
Volume
36
Category
Article
ISSN
0040-4039

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First [2+2]-cycloaddition of a 3,4-dideh
โœ Natacha Mariet; Malika Ibrahim-Ouali; Maurice Santelli ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 62 KB

The 3-or 4-halopyridines and a ketene dialkyl acetal were shown to permit the synthesis of pyrido[b]cyclobutene derivatives. This finding constitutes the first published report of cycloadditions involving an olefin and a 3,4-pyridyne partner. The reaction is totally regioselective and the structure