Stereospecific Synthesis, Structural Characterisation and Resolution of 2-Phospha[3]ferrocenophane Derivatives – a New Chiral Scaffold
✍ Scribed by Nicolas Fleury-Brégeot; Armen Panossian; Angèle Chiaroni; Angela Marinetti
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 202 KB
- Volume
- 2007
- Category
- Article
- ISSN
- 1434-1948
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Twenty-one of the chiral 4-alkoxycarbonyl-2-(␣-alkyl-␣-ethoxycarbonyl methylamino)-1,3-2-thia or oxazaphospholidine-2-ones have been synthesized by cyclization of L-serine or L-cysteine ethyl or n-octyl ester with phosphoryl chloride followed by reaction with a suitable L-amino acid ethyl ester. Pro