Stereospecific Synthesis of α-Substituted syn -α,β-Diamino Acids by the Diaza-Cope Rearrangement
✍ Scribed by Kim, Hyunwoo; Chin, Jik
- Book ID
- 121340812
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 432 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1523-7060
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## Abstract A novel method for the asymmetric synthesis of __α__,__β__‐diamino acids by using the 2,3,4,6‐tetra‐__O__‐pivaloyl‐__β__‐D‐glucopyranosyl group (Piv~4~Glc) as chiral auxiliary was developed (__Table__ and __Scheme__). The reaction was promoted by CuBr⋅Me~2~S as __Lewis__ acid, and high