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Stereospecific synthesis of the phosphonate isostere of 2-deoxyribose-3-phosphate

✍ Scribed by Palle V.P. Pragnacharyulu; Elie Abushanab


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
155 KB
Volume
36
Category
Article
ISSN
0040-4039

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## Abstract A general approach to isosteric phosphonate analogues of ulose‐l‐phosphates is described. A base‐catalysed chain elongation __via__ a __Michael__ addition of 1‐deoxy‐1‐nitro‐sugars **4, 8**, and **16** to the vinylphosphonate **18** followed by hydrolysis of the nitro adducts gave the a