Stereospecific synthesis of the cyclopenta [e] phenanthridine ring system: tetracyclic and pentacyclic analogues of cephalotaxus alkaloids

✍ Scribed by Martin R. Bryce; John M. Gardiner

• Book ID: 104203545
• Publisher: Elsevier Science
• Year: 1988
• Tongue: French
• Weight: 861 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(01)85847-6

✦ Synopsis

Methylenedioxy

and dimethoxy-derivatives of the hexahydrocyclopenta[e]phenanthridine ring system. (2la) and (21b). have been synthesised stereospecifically in six steps starting from piperonal (50% overall yield) and dimethoxybenzaldehyde (27% overall yield), respectively.